The Epigenetics Revolution: How Modern Biology is Rewriting Our Understanding of Genetics, Disease and Inheritance

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Carey’s experience of the biotechnology industry shows in her concluding remarks on the pros and cons of our growing understanding of epigenetics for drug discovery, and on understanding the impact of diet and environment on disease.

For Waddington, genetic assimilation was one the main ways in which epigenetic mechanisms were relevant to evolutionary change.Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. Nessa Carey has a gift for the expression of complicated scientific concepts in clear and simple terms and brings to life the personalities responsible for key advances.

Nessa Carey, a molecular biologist, explains all clearly, while sucking in the uninitiated with intriguing tales of queen bees, tortoiseshell cats, un-identical identical twins and lots more. Using the mammalian dentary as their example, they summarize what is known about the developmental basis for integration in that system.Everything you need to follow the argument is succinctly provided, without distracting excursions into other fields. I had no idea what Epigenetics was before reading this book but after getting just a couple of pages in I couldn’t believe how much I had been missing out on! In the factory, molten metal or plastic gets poured into the mould thousands of times and, unless something goes wrong in the process, out pop thousands of identical car parts. Nessa Carey has a virology PhD from the University of Edinburgh and is a former Senior Lecturer in Molecular Biology at Imperial College, London.

Photograph: MICHAEL KOOREN/REUTERS Nectar points … bees have phenomenal memories for such small creatures. Carey’s experience of the biotechnology industry shows in her concluding remarks on the pros and cons of our growing understand­ing of epigenetics for drug discovery, and on understanding the impact of diet and environment on disease. In this book, Nessa Carey describes how the world around you can and will influence everything about the way your body works by changing your genetic material. La descrizione dei processi dinamici che regolano la utilizzazione delle informazioni del DNA è fantastica.Chapters 3 and 4 give an overview of genetic and epigenetic molecular biology, including the genetic code, DNA replication, transcription, translation, chromatin, DNA methylation, and histone modifications. But then came the really surprising:babies who were born small tended to stay small all their lives - even though they were properly nourished - with lower obesity rates than the general population. This volume explores the dimensions of epigenetics in different systems and contexts to show the central place and explanatory power of the concept for evolutionary and developmental biology. The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice.